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  A New Approach
Explore CENIGENT’s Difference
  The 8 Vital Systems
Cell & Mitochondria
Endocrine System
Good News For Women
Nervous System
Immune System
Genetic System
What are SNPs?
Epigenetic System
Thought System
  Meet Lida Ghaderi MD
Dr. Ghaderi’s Letter to You
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The Genetic System

Genetics: Your Body’s Recipe Book… Evolving Over Generations to Tell Your Unique Story

Your genetic information is similar to a recipe book: a book that is written in a special language, with an alphabet of only 4 letters. DNA is the language, and the letters are A, C, G and T, called nucleotides or bases. Each word in the book is made of up only 3 letters and serves as a recipe to produce one amino acid. A chain of amino acids make up a protein.

One complete sentence, made of several words in this recipe book, provides the recipe to make one protein. Although an oversimplification given our current and evolving understanding of genes after the completion of the human genome project, this single sentence recipe that makes a single protein is called a gene. Your genes are protected in a special walled-off house called a nucleus within your cell.

Your body intuitively copies these specific recipes every time it needs to produce a protein. With 100,000 different proteins in your body, each one is read and manufactured from your genetic instruction manual.

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Your Unique SNPs Make all the Difference In Your Health and In CENIGENT

What Do Your Genes Do?

Your genes contain the biological information or characteristics your parents passed onto you and they control the entire growth and development of all your cells. Genes determine your physical features such as hair color, eye color and blood type, and also your risks of developing certain diseases. Subtle changes in your nucleotides, genes or chromosomes may cause defects or a decline in a variety of body functions.

Having a set of genes does not necessarily mean you will express these genes, nor does it mean that your body will automatically use a particular gene to make a protein. For instance, if you have a cookbook and you are running a restaurant, based on how many orders for Tiramisu or Chilean Sea Bass you receive, you’ll copy the recipe book accordingly and make just the right amount. Likewise, all the CENIGENT systems rely on the genetic recipe to make the proteins that each cell needs to run its operations successfully.

If your body is under chronic stress and inflammation, with low hormones levels and specific environmental toxins, your body will feel under attack and will use recipes that support an ongoing war: over production of stress hormones, inflammatory material and high energy requirement, leading to increased free radical damage.

What Are SNPs?

What if there’s a “typo” in the recipe book?

There can be slight variations in your DNA sequences which, when shared by at least 1% of the world population, is called a Single Nucleotide Polymorphism or SNP (pronounced “snip”). These SNPs are simply a change in a single letter of a “word” in the genetic recipe book, such as the letter A being substituted for C. Each person can have 1 to 2 million SNPs.

SNPs can have a major impact on:

  • Whether or not we develop a disease.
  • How we respond to food.
  • Reactions to environmental insults such as bacteria, viruses and toxins.
  • Acceptance, absorption or reaction to certain therapies, drugs and hormones.

It is this micro level of testing and research that sets CENIGENT apart from other programs and practices. By testing some of your SNPs and being at the forefront of cutting-edge research, your CENIGENT doctor can recommend better and safer personalized therapies, bio-identical hormone restoration, targeted nutritional supplementation, pharmaceutical drugs and dietary recommendations that will help prevent diseases for which you are at risk. SNPs will also help your doctor improve and optimize your health if you already have certain conditions.

Our Differences Matter More Than We Thought—SNPs & The Advent of Personalized Medicine

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Our SNPs, inherited subtle genetic variations, can be the difference, for example, in how estrogen is broken down and disposed of, how well we each will tolerate estrogen and what negative consequences it may have for both women and men.

Both men and women have estrogen. However, once the body uses the estrogen, it must be disposed of by being broken down in stages.

The two major players in the clearance process are enzyme groups which, for simplicity sake, we will call CYP and COMT.

Some SNPs can cause CYP and COMT to work either slower or faster than usual.

Estrogen is first broken down by CYP to predominantly a toxic waste product which, if not properly disposed of, can damage to genes and increase the risk of many cancers, including breast cancer in women and prostate cancer or enlargement in men.

Next, COMT will take this dangerous estrogen compound made by CYP and will change it so it can be easily disposed of. COMT can also make a form of estrogen which actually is beneficial in preventing breast cancer.

Imagine you have had a wonderful celebration bash on an exotic island and have a great deal of trash to dispose of. You hire two native people called CYP and COMT. CYP is responsible to burn the trash and COMT is responsible to pour water on the burned trash. If CYP works very fast and COMT works very slow, it becomes a dangerous combination - uncontrolled fire and not enough water to extinguish it.

A similar event can occur in your body. Your genetic variations determine how quickly CYP and COMT work. If you have the SNP which increases CYP and slows COMT, it can increase your risk of cancer and many other adverse health conditions.


SNPs do not cause disease, but they can help predict if someone will develop a particular disease well in advance of the disease's onset.

SNPs increase the safety of our hormone replacement therapies

Using specific genetic polymorphism testing is essential to identify these inherited variations and to create a safe personalized hormone restoration program. It is this level of genetic testing and research that separates and distinguishes CENIGENT’s Endocrine Optimization Program from the many other hormone replacement therapy programs available.

CENIGENT includes SNP testing in your comprehensive assessment

Wouldn't you like to know that the treatments you are undergoing are custom-designed just for you, right down to your unique genetic code?

At CENIGENT, we wouldn’t have it any other way…


You may also want to download and read  “Age Less. Live More. The Get Started Guide to Restoring and Enjoying Peak Health” to learn more about the CENIGENT Enhancement Program and whether it is right for you.

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